Ben-Yosef Tamar - Associate Professor

ben-yosef tamar

Main Research Area

Work in my lab is focused on the genetic basis for hereditary vision and hearing loss. I study human patients and mouse models for human disease. My work is based on various molecular biology techniques, and is a combination of classic techniques in human genetics (mapping, sequencing), cell biology, and working with mice

 Research projects

Genetics of Vision and Hearing Loss

Journal articles

Haer-Wigman L, Newman H, Leibu R, Bax NM, Baris HN, Rizel L, Banin E, Massarweh A, Roosing S, Lefeber DJ, Zonneveld-Vrieling MN, Isakov O, Shomron N, Sharon D, Den Hollander AI, Hoyng CB, Cremers FP, Ben-Yosef T.
Non-syndromic retinitis pigmentosa due to mutations in the mucopolysaccharidosis type IIIC gene, heparan-alpha-glucosaminide N-acetyltransferase (HGSNAT). Hum Mol Genet. 2015 ;24(13):3742-51

Remez L, Zobor D, Kohl S, Ben-Yosef T.
The progressive rod-cone degeneration (PRCD) protein is secreted through the conventional ER/Golgi-dependent pathway. Exp Eye Res. 2014;125:217-25.

Nevet MJ, Vekslin S, Dizhoor AM, Olshevskaya EV, Tidhar R, Futerman AH, Ben-Yosef T.
Ceramide kinase-like (CERKL) interacts with neuronal calcium sensor proteins in the retina in a cation-dependent manner. Invest Ophthalmol Vis Sci. 2012;53(8):4565-74.

Vekslin S, Ben-Yosef T.
Spatiotemporal expression pattern of ceramide kinase-like in the mouse retina. Mol Vis. 2010;16:2539-49.

Dvir L, Srour G, Abu-Ras R, Miller B, Shalev SA, Ben-Yosef T.
Autosomal-recessive early-onset retinitis pigmentosa caused by a mutation in PDE6G, the gene encoding the gamma subunit of rod cGMP phosphodiesterase. Am J Hum Genet. 2010;87(2):258-64.